Potassium Bitartrate
Potassium Bitartrate Uses, Dosage, Side Effects, Food Interaction and all others data.
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer, pH control agent, antimicrobial agent, processing aid, or thickener in various food products . Potassium Bitartrate has a long history of medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in Japan.
Potassium Bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Potassium Bitartrate potentiates bowel movements. In medical studies, it was shown to be an effective treatment for chronic constipationwhen combined with sodium bicarbonate in a polyethylene glycol-based suppository .
Trade Name | Potassium Bitartrate |
Generic | Potassium bitartrate |
Potassium bitartrate Other Names | Potassium bitartrate, potassium hydrogen tartrate |
Type | |
Formula | C4H5KO6 |
Weight | Average: 188.176 Monoisotopic: 187.97231937 |
Protein binding | No pharmacokinetic data available. |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Potassium Bitartrate is a laxative used to treat constipation.
Indicated for the treatment of constipation.
Potassium Bitartrate is also used to associated treatment for these conditions: Chemical contraception
How Potassium Bitartrate works
Potassium Bitartrate is a carbon dioxide-releasing laxative that works by forming carbon dioxide gas, which creates a mechanical distension against the intestinal wall and induces bowel contractions. Rectal suppositories of carbon dioxide-releasing type of laxative were demonstrated to be useful and safe in the treatment of patients at risk for electrolyte disorders such as the elderly or patients with renal or cardiovascular disorders .
Toxicity
Lowest published lethal dose in rat via oral route is 22000 mg/kg . Cases of hyperkalemia have been reported with ingestion of a large quantity of potassium bitartrate .
Volume of Distribution
No pharmacokinetic data available.
Elimination Route
There is little systemic absorption expected following rectal administration of potassium bitartrate.
Half Life
No pharmacokinetic data available.
Clearance
No pharmacokinetic data available.
Elimination Route
No pharmacokinetic data available.
Innovators Monograph
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