Potassium Hydrogen Tartrate

Potassium Hydrogen Tartrate Uses, Dosage, Side Effects, Food Interaction and all others data.

Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer, pH control agent, antimicrobial agent, processing aid, or thickener in various food products . Potassium Hydrogen Tartrate has a long history of medical use as a laxative administered as a rectal suppository and is an approved third-class OTC drug in Japan.

Potassium Hydrogen Tartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.

Potassium Hydrogen Tartrate potentiates bowel movements. In medical studies, it was shown to be an effective treatment for chronic constipationwhen combined with sodium bicarbonate in a polyethylene glycol-based suppository .

Trade Name Potassium Hydrogen Tartrate
Generic Potassium bitartrate
Potassium bitartrate Other Names Potassium bitartrate, potassium hydrogen tartrate
Type
Formula C4H5KO6
Weight Average: 188.176
Monoisotopic: 187.97231937
Protein binding

No pharmacokinetic data available.

Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Potassium Hydrogen Tartrate
Potassium Hydrogen Tartrate

Uses

Potassium Hydrogen Tartrate is a laxative used to treat constipation.

Indicated for the treatment of constipation.

Potassium Hydrogen Tartrate is also used to associated treatment for these conditions: Chemical contraception

How Potassium Hydrogen Tartrate works

Potassium Hydrogen Tartrate is a carbon dioxide-releasing laxative that works by forming carbon dioxide gas, which creates a mechanical distension against the intestinal wall and induces bowel contractions. Rectal suppositories of carbon dioxide-releasing type of laxative were demonstrated to be useful and safe in the treatment of patients at risk for electrolyte disorders such as the elderly or patients with renal or cardiovascular disorders .

Toxicity

Lowest published lethal dose in rat via oral route is 22000 mg/kg . Cases of hyperkalemia have been reported with ingestion of a large quantity of potassium bitartrate .

Volume of Distribution

No pharmacokinetic data available.

Elimination Route

There is little systemic absorption expected following rectal administration of potassium bitartrate.

Half Life

No pharmacokinetic data available.

Clearance

No pharmacokinetic data available.

Elimination Route

No pharmacokinetic data available.

Innovators Monograph

You find simplified version here Potassium Hydrogen Tartrate

*** Taking medicines without doctor's advice can cause long-term problems.
Share