Practolol Uses, Dosage, Side Effects and more
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Practolol is a beta-adrenergic receptor antagonist that has been used in the emergency treatment of cardiac arrhythmias. Beta blockers inhibit normal epinephrine-mediated sympathetic actions, but have minimal effect on resting subjects. That is, they reduce the effect of excitement/physical exertion on heart rate and force of contraction and dilation of blood vessels.
| Attribute | Details |
|---|---|
| Trade Name | Practolol |
| Generic | Practolol |
| Practolol Other Names | Practolol, Practololo, Practololum, Praktololu |
| Type | |
| Formula | C14H22N2O3 |
| Weight | Average: 266.3361 Monoisotopic: 266.16304258 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Used in the emergency treatment of cardiac arrhythmias.
How Practolol works
Like other beta-adrenergic antagonists, practolol competes with adrenergic neurotransmitters such as catecholamines for binding at sympathetic receptor sites. Like propranolol and timolol, practolol binds at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting the effects of the catecholamines epinephrine and norepinephrine and decreasing heart rate, cardiac output, and systolic and diastolic blood pressure.
Toxicity
Symptoms of overdose include abdominal irritation, central nervous system depression, coma, extremely slow heartbeat, heart failure, lethargy, low blood pressure, and wheezing.
Food Interaction
- Avoid alcohol.
- Avoid natural licorice.
