Prax Wipe
Prax Wipe Uses, Dosage, Side Effects, Food Interaction and all others data.
Prax Wipe (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Prax Wipe is available by itself and in combination with other medications in various topical preparations. It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation.
Prax Wipe temporarily relieves pain, pruritis, burning and discomfort associated with minor lip and skin irritations and hemorrhoid's by inhibiting voltage gated sodium channels on neurons.
| Trade Name | Prax Wipe |
| Generic | Pramocaine |
| Pramocaine Other Names | Pramocaína, Pramocaine, Pramoxine |
| Weight | 1%, 1%, 1%, 1%, 1%, 1%, 1% |
| Type | Rectal foam, topical cream, topical gel, topical lotion, topical pad, topical spray, topical stick |
| Formula | C17H27NO3 |
| Weight | Average: 293.407 Monoisotopic: 293.199093733 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Prax Wipe is a local anesthetic and antipruritic agent found in various topical preparations.
It is indicated for temporary relief of pain and pruritus from minor lip and skin irritations as well as for temporary relief from pain, burning, itching and discomfort associated with hemorrhoids and other anorectal/anogenital disorders.
Prax Wipe is also used to associated treatment for these conditions: Dermatosis, Hemorrhoids, Itching of the perianal area, Skin Irritation
How Prax Wipe works
Prax Wipe reversibly binds and inhibits voltage gated sodium channels on neurons decreasing sodium permeability into the cell. This stabilizes the membrane and prevents ionic fluctuations needed for depolarization stopping any action potential propagation.
Toxicity
LD50 Mouse ip 300 mg/kg, LD50 Mouse sc 750 mg/kg
Food Interaction
No interactions found.Elimination Route
There is minimal absorption after topical administration and it is not given orally.
Innovators Monograph
You find simplified version here Prax Wipe
FAQ
What is Prax Wipe use for?
Prax Wipe is used to decrease swelling, itching and pain that is caused by minor skin irritations or hemorrhoids.It also used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders.
How safe Prax Wipe is?
Prax Wipe is a safe, steroid-free, itch-relieving option that can be used as needed.
What are the common side effects of Prax Wipe?
Prax Wipe may cause side effects include:
- redness, irritation, swelling, burning, stinging, or pain at affected area.
- dryness at affected area.
How long can I use Prax Wipe?
Do not use Prax Wipe for more than 14 days. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.Do not use your medicine more often than directed.
Is Prax Wipe safe for pregnancy?
Prax Wipe topical should only be given during pregnancy when benefits outweigh risks Prax Wipe topical has not been formally assigned to a pregnancy category by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy.
Can I take Prax Wipe with alcohol?
You should avoid alcohol while you're taking Prax Wipe. You should continue to avoid alcohol for 48 hours after you stop taking medication.
Is Prax Wipe safe for babies?
Prax Wipe may safe younger than 2 years baby .Do not use Prax Wipe for skin irritation in children younger than 2 years unless directed by the doctor.
How long does it take for Prax Wipe to work?
Clinical studies have shown that Prax Wipe hydrochloride begins working in as little as two minutes, and its effects last for up to eight hours.
How many times a day can I use Prax Wipe cream?
Prax Wipe cream/ointment use once or twice a day. It must not be applied more often than twice a day, and once a day is often sufficient.
Can i use Prax Wipe on my face?
Prax Wipe can be used to help relieve itching on the face and body.
How long can I use Prax Wipe?
You should not use for more than 14 days.
How does Prax Wipe work?
It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation.Prax Wipe is available by itself and in combination with other medications in various topical preparations.
Is Prax Wipe an anti inflammatory?
Prax Wipe is a topical aerosol foam containing a corticosteroid used as an anti-inflammatory/anti-itch agent and a local anesthetic used to relieve inflammatory and itching manifestations of corticosteroid-responsive skin conditions .
Is Prax Wipe good for hemorrhoids?
Prax Wipe is an anesthetic, or numbing medicine. Prax Wipe is used to treat pain or itching caused by insect bites, minor burns or scrapes, hemorrhoids, vaginal irritation, and minor skin rash, dryness, or itching.
Does Prax Wipe stop itching?
Topical treatments that contain hydrochloride can be applied directly to the source of the itch and can, therefore, work to relieve the itch quickly.
Is Prax Wipe a vasoconstrictor?
There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
How does Prax Wipe work?
Prax Wipe is a drug that aids the body's mucus-clearing processes in the respiratory tract. It is used to relieve chest congestion. This medicine works by blocking a certain natural substance (known as histamine) that your body makes during an allergic reaction.
