Precef

Precef Uses, Dosage, Side Effects, Food Interaction and all others data.

Precef is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species.

Precef is a semisynthetic second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins.

Table Of contents

• Precef
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Precef
Generic	Ceforanide
Ceforanide Other Names	Ceforanide, Ceforanido, Ceforanidum
Weight	500mg,
Type	Injection
Formula	C20H21N7O6S2
Weight	Average: 519.554 Monoisotopic: 519.099472819
Protein binding	80.6%
Groups	Approved
Therapeutic Class
Manufacturer	Glaxosmithkline, Prem Pharmaceuticals Ltd
Available Country	Pakistan, India,
Last Updated:	September 19, 2023 at 7:00 am

Uses

For the treatment of infections caused by susceptible organisms.

How Precef works

The bactericidal activity of ceforanide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).

Toxicity

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Elimination Route

Rapidly absorbed following intramuscular injection.

Half Life

2.6 to 2.98 hours

Innovators Monograph

You find simplified version here Precef