Precef

Precef Uses, Dosage, Side Effects, Food Interaction and all others data.

Precef is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species.

Precef is a semisynthetic second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins.

Trade Name Precef
Generic Ceforanide
Ceforanide Other Names Ceforanide, Ceforanido, Ceforanidum
Weight 500mg,
Type Injection
Formula C20H21N7O6S2
Weight Average: 519.554
Monoisotopic: 519.099472819
Protein binding

80.6%

Groups Approved
Therapeutic Class
Manufacturer Glaxosmithkline, Prem Pharmaceuticals Ltd
Available Country Pakistan, India,
Last Updated: September 19, 2023 at 7:00 am
Precef
Precef

Uses

For the treatment of infections caused by susceptible organisms.

How Precef works

The bactericidal activity of ceforanide results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).

Toxicity

Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.

Elimination Route

Rapidly absorbed following intramuscular injection.

Half Life

2.6 to 2.98 hours

Innovators Monograph

You find simplified version here Precef

*** Taking medicines without doctor's advice can cause long-term problems.
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