Prilocaine Base

Prilocaine Base Uses, Dosage, Side Effects, Food Interaction and all others data.

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

Prilocaine Base binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. Action potential propagation and never function is, therefore, prevented. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns.

Prilocaine Base
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Prilocaine Base
Availability	Discontinued
Generic	Prilocaine
Prilocaine Other Names	Prilocain, Prilocaina, Prilocaïne, Prilocaine, Prilocaine base, Prilocainum, Propitocaine
Type
Formula	C₁₃H₂₀N₂O
Weight	Average: 220.3107 Monoisotopic: 220.157563272
Protein binding	98%
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Prilocaine Base is a local anesthetic used in dental procedures.

Used as a local anaesthetic and is often used in dentistry.

Prilocaine Base is also used to associated treatment for these conditions: Local anesthesia therapy

How Prilocaine Base works

Prilocaine Base acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers.

Food Interaction

Take separate from meals. This is only required when prilocaine is used in the mouth, as it may cause numbness, which can cause bite injury when eating.