Probrin
Probrin Uses, Dosage, Side Effects, Food Interaction and all others data.
Probrin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.
Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.
| Trade Name | Probrin |
| Availability | Discontinued |
| Generic | Protirelin |
| Protirelin Other Names | Protirelin, Protirelina, Thyroliberin, Thyrotropic releasing hormone, Thyrotropic-releasing factor, Thyrotropin releasing hormone, Thyrotropin-releasing factor, TSH-releasing factor, TSH-releasing hormone |
| Weight | 0.732mg |
| Type | Injection |
| Formula | C16H22N6O4 |
| Weight | Average: 362.3837 Monoisotopic: 362.170253222 |
| Groups | Approved, Investigational |
| Therapeutic Class | |
| Manufacturer | Medisure Laboratories Pakistan (pvt,) Ltd, |
| Available Country | Pakistan |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Probrin is a synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland.
Food Interaction
- Do not take with or immediately after a high-fat meal. Fatty food can disrupt the TSH assay by increasing lipid levels in the blood.
- Take with or without food. Take protirelin either after a low-fat meal or on an empty stomach.
Innovators Monograph
You find simplified version here Probrin
