R411 Uses, Dosage, Side Effects and more
R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7.
| Attribute | Details |
|---|---|
| Trade Name | R411 |
| Generic | R411 |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in asthma.
How R411 works
R411 prevents binding of V-CAM1 to either a4b1 or a4b7.
Toxicity
Good safety profile observed in preclinical and clinical studies
