Recombinant Nematode Anticoagulant Protein C2 Uses, Dosage, Side Effects and more
Recombinant nematode anticoagulant protein c2 (Recombinant Nematode Anticoagulant Protein C2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity.
| Trade Name | Recombinant Nematode Anticoagulant Protein C2 |
| Generic | rNAPc2 |
| rNAPc2 Other Names | Recombinant nematode anticoagulant protein c2, Recombinant nematode anticoagulant protein-2 |
| Type | |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Investigated for use/treatment in thrombosis (deep vein), angina, coronary artery disease, and colorectal cancer.
How Recombinant Nematode Anticoagulant Protein C2 works
Recombinant Nematode Anticoagulant Protein c2 (Recombinant Nematode Anticoagulant Protein C2) is a potent (K(i) =10 pM), inhibitor of the factor VIIa/tissue factor (fVIIa/TF) complex that requires the prerequisite binding to zymogen or activated factor X (fX). This has been shown to attenuate the activation of coagulation and to prevent death in a primate model of sepsis caused by gram-negative bacteria.
Half Life
Over 50 hours
