Recombinant Nematode Anticoagulant Protein C2
Recombinant Nematode Anticoagulant Protein C2 Uses, Dosage, Side Effects, Food Interaction and all others data.
Recombinant nematode anticoagulant protein c2 (Recombinant Nematode Anticoagulant Protein C2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity.
Trade Name | Recombinant Nematode Anticoagulant Protein C2 |
Generic | rNAPc2 |
rNAPc2 Other Names | Recombinant nematode anticoagulant protein c2, Recombinant nematode anticoagulant protein-2 |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in thrombosis (deep vein), angina, coronary artery disease, and colorectal cancer.
How Recombinant Nematode Anticoagulant Protein C2 works
Recombinant Nematode Anticoagulant Protein c2 (Recombinant Nematode Anticoagulant Protein C2) is a potent (K(i) =10 pM), inhibitor of the factor VIIa/tissue factor (fVIIa/TF) complex that requires the prerequisite binding to zymogen or activated factor X (fX). This has been shown to attenuate the activation of coagulation and to prevent death in a primate model of sepsis caused by gram-negative bacteria.
Half Life
Over 50 hours
Innovators Monograph
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