Sanvar IR
Sanvar IR Uses, Dosage, Side Effects, Food Interaction and all others data.
Sanvar IR is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Sanvar IR is a somatostatin analog with a higher metabolic stability than the parent hormone. Sanvar IR reduces splanchnic blood flow; inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.
Trade Name | Sanvar IR |
Generic | Vapreotide |
Vapreotide Other Names | Vapreotida, Vapreotide, Vapreotidum |
Type | |
Formula | C57H70N12O9S2 |
Weight | Average: 1131.38 Monoisotopic: 1130.48301423 |
Groups | Experimental, Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
How Sanvar IR works
The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesic effects of vapreotide (PMID: 7556407).
Toxicity
Safety data are limited, however, headache, fatigue, diarrhea, nausea, vomiting, and abdominal pain have been reported commonly with the use of vapreotide.
Half Life
30 minutes
Elimination Route
Sanvar IR is 76% eliminated in bile. The remainder is renally eliminated.
Innovators Monograph
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