Stanate

Stanate Uses, Dosage, Side Effects, Food Interaction and all others data.

Stanate is a competitive heme oxygenase (HO) inhibitor being developed by InfaCare, a subsidiary of WellSpring Pharmaceuticals, for the prevention of hyperbilirubinemia in infants at risk of developing jaundice.

Stanate is a chemical compound being investigated for use as a medicament in the treatment of infant jaundice. Stanate is also known to inhibit heme metabolism in mammals, to control the rate of tryptophan metabolism in mammals, and to increase the rate at which heme is excreted by mammals.

Stanate
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
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Trade Name	Stanate
Generic	Stannsoporfin
Stannsoporfin Other Names	Stannsoporfin, Tin mesoporphyrin
Type
Formula	C₃₄H₃₆Cl₂N₄O₄Sn
Weight	Average: 754.3 Monoisotopic: 754.113563
Groups	Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Investigated for use/treatment in liver disease, metabolic disease, and pediatric indications.

How Stanate works

Kernicterus is attributed to high levels of bilirubin, a by-product of heme metabolism. Bilirubin is a bile pigment, which is normally eliminated from the body after conversion into a water-soluble form by the liver. Stanate's mechanism of action specifically inhibits the enzyme that blocks the conversion of heme into bilirubin.