Simox DS Powder for Suspension 250 mg/5 ml

Simox DS Powder for Suspension 250 mg/5 ml Uses, Dosage, Side Effects, Food Interaction and all others data.

Table Of contents

• Simox DS Powder for Suspension 250 mg/5 ml
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Simox DS Powder for Suspension 250 mg/5 ml
Generic	Amoxicillin Trihydrate
Weight	250 mg/5 ml
Type	Powder for Suspension
Therapeutic Class	Broad spectrum penicillins
Manufacturer	Silva Pharmaceuticals Ltd.
Available Country	Bangladesh
Last Updated:	October 19, 2023 at 6:27 am

Uses

Amoxicillin is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis) Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis) ... Read more

Dosage

Simox DS Powder for Suspension 250 mg/5 ml dosage

Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections.Children (up to 10 years of age) : 125 mg three times daily, increasing up to 250 mg three times daily for severe infections. Severe or recurrent purulent respiratory infection: 3 gm every 12 hours. Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily). Pneumonia: Recommended dose is 500-1000 mg three times daily. Dental abscess: Recommended dose is 3 gm, repeated after 10-12 hours. Urinary tract infections: Recommended dose is 3 gm, repeated after 10-12 hours. Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years). In renal impairment:it may be necessary to reduce the total daily dosage. Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water. These preparations should then be taken immediately.

Side Effects

Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.

Precaution

The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoxicillin should be discontinued and appropriate therapy should be instituted.

Interaction

Concurrent use of Amoxicillin and Probenecid may result in increased and prolonged blood levels of Amoxicillin. Amoxicillin may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.

Pregnancy & Breastfeeding use

US FDA pregnancy category of Amoxicillin is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Amoxicillin has been shown to be excreted in human milk. So, caution should be exercised when Amoxicillin is administered to a lactating mother.

Contraindication

Amoxicillin is contraindicated in penicillin hypersensitive patients.

Storage Condition

Keep in a dry place away from light and heat. Keep out of the reach of children.

Innovators Monograph

You find simplified version here Simox DS Powder for Suspension 250 mg/5 ml