Solfametopirazina

Solfametopirazina Uses, Dosage, Side Effects, Food Interaction and all others data.

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.

Solfametopirazina is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Table Of contents

• Solfametopirazina
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Solfametopirazina
Generic	Sulfametopyrazine
Sulfametopyrazine Other Names	Solfametopirazina, Sulfalene, Sulfaleno, Sulfalenum, Sulfamethopyrazine
Type
Formula	C11H12N4O3S
Weight	Average: 280.303 Monoisotopic: 280.06301096
Groups	Approved, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Solfametopirazina is an antibiotic used in the treatment or prevention of bacterial infections and malaria.

For the treatment of urinary tract infection and chronic bronchitis.

Solfametopirazina is also used to associated treatment for these conditions: Plasmodium Infections

How Solfametopirazina works

Solfametopirazina is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Para-aminobenzoic acid (PABA), a substrate of the enzyme is prevented from binding. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

Innovators Monograph

You find simplified version here Solfametopirazina