SR-123781A
SR-123781A Uses, Dosage, Side Effects, Food Interaction and all others data.
SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Trade Name | SR-123781A |
Generic | SR-123781A |
Type | |
Formula | C127H201Na37O134S17 |
Weight | Average: 5267.5 Monoisotopic: 5264.02818943 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in cardiovascular disorders, thrombosis, and venous thromboembolism.
How SR-123781A works
SR123781A is a synthetic hexadecasaccharide comprising an antithrombin (AT) binding domain, a thrombin binding domain, and a neutral methylated hexasaccharide sequence, was obtained from glucose through a convergent synthesis. SR123781A showed high affinity for human AT and was a potent catalyst of its inhibitory effect with regard to factor Xa and thrombin.
Innovators Monograph
You find simplified version here SR-123781A