Sulfametazyny

Sulfametazyny Uses, Dosage, Side Effects, Food Interaction and all others data.

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.

Sulfametazyny is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfametazyny is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA.

Table Of contents

• Sulfametazyny
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Sulfametazyny
Generic	Sulfamethazine
Sulfamethazine Other Names	Sulfadimethyldiazine, Sulfadimethylpyrimidine, Sulfadimidina, Sulfadimidine, Sulfadimidinum, Sulfametazina, Sulfametazyny, Sulfamethazine, Sulfamezathine, Sulphadimethylpyrimidine, Sulphamethazine
Type
Formula	C12H14N4O2S
Weight	Average: 278.33 Monoisotopic: 278.083746402
Groups	Approved, Investigational, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Sulfametazyny is an antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.

For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.

Sulfametazyny is also used to associated treatment for these conditions: Bacterial Conjunctivitis, Endometritis, Furuncle, Streptococcal Sore Throat, Ulcers, Urinary Tract Infection

How Sulfametazyny works

Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.

Toxicity

Sulfametazyny may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns.

Food Interaction

No interactions found.

Elimination Route

Rapidly absorbed following oral administration.

Innovators Monograph

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