Sulphamerazine

Sulphamerazine Uses, Dosage, Side Effects, Food Interaction and all others data.

A sulfanilamide that is used as an antibacterial agent.

Sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis in bacteria.

Trade Name Sulphamerazine
Generic Sulfamerazine
Sulfamerazine Other Names Sulfamerazina, Sulfamerazine, Sulfamerazinum, Sulfamethyldiazine, Sulphamerazine
Type
Formula C11H12N4O2S
Weight Average: 264.304
Monoisotopic: 264.068096338
Groups Approved, Vet approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Sulphamerazine
Sulphamerazine

Uses

Sulphamerazine is an antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.

A sulfanilamide that is used as an antibacterial agent. It can be used to treat bronchitis, prostatitis and urinary tract infections.

Sulphamerazine is also used to associated treatment for these conditions: Abscesses, Conjunctivitis, Ear infection bacterial, Enteritis, Eye Infections, Eye discharge, Pneumonia, Streptococcal Sore Throat, Susceptible infections, Ulcers, Urinary Tract Infection, Urinary tract inflammation, Uterine infection

How Sulphamerazine works

Sulphamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulphamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA.

Toxicity

Sulphamerazine may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns.

Food Interaction

No interactions found.

Elimination Route

Rapidly absorbed following oral administration.

Innovators Monograph

You find simplified version here Sulphamerazine

*** Taking medicines without doctor's advice can cause long-term problems.
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