Ticalopride

Ticalopride Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Ticalopride
Generic Ticalopride
Ticalopride Other Names Norcisapride, Ticalopride
Type
Formula C14H20ClN3O3
Weight Average: 313.78
Monoisotopic: 313.119319228
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Ticalopride
Ticalopride

Uses

Investigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.

How Ticalopride works

Ticalopride is an isomer of the active metabolite of cisapride. Cisapride acts through the stimulation of the serotonin 5-HT4 receptors which increases acetylcholine release in the enteric nervous system (specifically the myenteric plexus). This results in increased tone and amplitude of gastric (especially antral) contractions, relaxation of the pyloric sphincter and the duodenal bulb, and increased peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit.

Innovators Monograph

You find simplified version here Ticalopride

*** Taking medicines without doctor's advice can cause long-term problems.
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