Tribiocillina
Tribiocillina Uses, Dosage, Side Effects, Food Interaction and all others data.
A macrolide antibiotic that is similar to erythromycin.
Tribiocillina, like other macrolide antibiotics, inhibits bacterial protein synthesis to prevent growth.
| Trade Name | Tribiocillina |
| Availability | Discontinued |
| Generic | Troleandomycin |
| Troleandomycin Other Names | Oleandocetine, Oleandomycin triacetate, Oleandomycin triacetyl ester, Triacetyloleandomycin, Triacetyloleandomycinum, Tribiocillina, Troleandomicina, Troleandomycin, Troleandomycine |
| Related Drugs | amoxicillin, doxycycline, ciprofloxacin, metronidazole, azithromycin, clindamycin, levofloxacin, Levaquin, penicillin v potassium, Bicillin L-A |
| Type | |
| Formula | C41H67NO15 |
| Weight | Average: 813.9684 Monoisotopic: 813.451070479 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
For the treatment of bacterial infection.
How Tribiocillina works
As a macrolide, troleandomycin binds to the 50S subunit of the bacterial ribosome . This binding inhibits translocation of tRNA along the A, P, and E sites of the ribosome. With tRNA unable to move from site to site, amino acids cannot be deposited onto the polypeptide chain leading to failure of protein synthesis. Bacterial cell growth and duplication is inhibited without the ability to generate the necessary proteins.
Toxicity
Tribiocillina inhibits clearance of theophylline and can increase the likelyhood of toxicity in patients recieving theophylline therapy .
Tribiocillina Disease Interaction
Innovators Monograph
You find simplified version here Tribiocillina
