Tricosal Uses, Dosage, Side Effects and more
Tricosal is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% .
Trisalicylate-choline is a non-steroidal anti-inflammatory drug (NSAID) that contains a combination of choline salicylate and magnesium salicylate. Does not affect platelet aggregation.
| Attribute | Details |
|---|---|
| Trade Name | Tricosal |
| Generic | Choline magnesium trisalicylate |
| Weight | 500mg/5ml, 1000mg, 500mg, 750mg, |
| Type | Oral liquid, oral tablet |
| Formula | C26H29MgNO10 |
| Weight | Average: 539.814 Monoisotopic: 539.164188051 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | United States, |
| Last Updated: | January 7, 2025 at 1:49 am |
Uses
Tricosal is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
Tricosal is also used to associated treatment for these conditions: Arthritis, Fever, Juvenile Idiopathic Arthritis (JIA), Mild pain, Osteoarthritis (OA), Rheumatoid Arthritis, Acute Shoulder Pain, Moderate Pain
How Tricosal works
Inhibits prostaglandin synthesis; acts on the hypothalamus heat-regulating center to reduce fever; blocks the generation of pain impulses
Toxicity
Salicylate intoxication, known as salicylism, may occur with large doses or extended therapy. Common symptoms of salicylism include headache, dizziness, tinnitus, hearing impairment, confusion, drowsiness, sweating, vomiting, diarrhea, and hyperventilation. A more severe degree of salicylate intoxication can lead to CNS disturbances, alteration in electrolyte balance, respiratory and metabolic acidosis, hyperthermia, and dehydration.
Elimination Route
renal
