Trodusquemine

Trodusquemine Uses, Dosage, Side Effects, Food Interaction and all others data.

Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B. It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models .

Trade Name Trodusquemine
Generic Trodusquemine
Trodusquemine Other Names Trodusquemine
Type
Formula C37H72N4O5S
Weight Average: 685.07
Monoisotopic: 684.522342608
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Trodusquemine
Trodusquemine

Uses

Investigated for use/treatment in obesity and diabetes mellitus type 2.

How Trodusquemine works

Trodusquemine is a spermine metabolite of cholesterol which possibly acts on the paraventricular nucleus in the hypothalamus. Trodusquemine suppresses feeding, prevents reduction in energy expenditure, causes hormonal changes, and induces patterns of neuropeptide expression normally associated with weight loss. Trosdusquemine enhances insulin sensitivity through inhibition of protein tyrosine phostphatase 1B centrally and peripherally (PTP-1B), dopamine and norepinephrine reuptake, an ion transport modulator and a downregulator of Agouti-related peptide (AgRP) and neuropeptide Y (NPY) expression.

Innovators Monograph

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