Trodusquemine
Trodusquemine Uses, Dosage, Side Effects, Food Interaction and all others data.
Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B. It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models .
Trade Name | Trodusquemine |
Generic | Trodusquemine |
Trodusquemine Other Names | Trodusquemine |
Type | |
Formula | C37H72N4O5S |
Weight | Average: 685.07 Monoisotopic: 684.522342608 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in obesity and diabetes mellitus type 2.
How Trodusquemine works
Trodusquemine is a spermine metabolite of cholesterol which possibly acts on the paraventricular nucleus in the hypothalamus. Trodusquemine suppresses feeding, prevents reduction in energy expenditure, causes hormonal changes, and induces patterns of neuropeptide expression normally associated with weight loss. Trosdusquemine enhances insulin sensitivity through inhibition of protein tyrosine phostphatase 1B centrally and peripherally (PTP-1B), dopamine and norepinephrine reuptake, an ion transport modulator and a downregulator of Agouti-related peptide (AgRP) and neuropeptide Y (NPY) expression.
Innovators Monograph
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