Valopicitabine Uses, Dosage, Side Effects and more

The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication. [from NCI]

Trade Name Valopicitabine
Generic Valopicitabine
Valopicitabine Other Names Valopicitabina, Valopicitabine
Type
Formula C15H24N4O6
Weight Average: 356.379
Monoisotopic: 356.169584509
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am

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