Varespladib Methyl Ester
Varespladib Methyl Ester Uses, Dosage, Side Effects, Food Interaction and all others data.
Varespladib Methyl Ester has been investigated for the treatment of Acute Coronary Syndrome. Studies showed that Varespladib Methyl Ester treatment resulted in significant positive changes on lipoproteins and inflammation.
| Trade Name | Varespladib Methyl Ester |
| Generic | Varespladib methyl |
| Varespladib methyl Other Names | Varespladib methyl, Varespladib methyl ester |
| Type | |
| Formula | C22H22N2O5 |
| Weight | Average: 394.427 Monoisotopic: 394.152871816 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in atherosclerosis and coronary artery disease.
How Varespladib Methyl Ester works
A–002 is an orally administered‚ potent inhibitor of secretory phospholipase spla2(spla2)‚ including groups IIA‚ V‚ and X. Atherosclerosis is a disease of the arteries that results from inflammation and the build-up of plaque under the lining of the blood vessel. This build-up can cause vascular swelling and eventual rupture. spla2 levels have been shown to be elevated in patients with both stable and unstable coronary artery disease. Higher levels of the enzyme have been shown to predict an increased risk for future cardiovascular events such as heart attacks and stroke.
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