Vintafolide
Vintafolide Uses, Dosage, Side Effects, Food Interaction and all others data.
Vintafolide is a folate-targeted chemotherapeutic conjugate (folate vitamin + vinca alkaloid) in clinical stage development as a treatment for folate-receptor positive cancers.
Trade Name | Vintafolide |
Generic | Vintafolide |
Vintafolide Other Names | Vintafolide |
Type | |
Formula | C86H109N21O26S2 |
Weight | Average: 1917.06 Monoisotopic: 1915.729405062 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in solid tumors.
How Vintafolide works
Vintafolide minimizes the off-target toxicity by delivering the vinca molecule directly and specifically to cancer cells that over-express the folate-receptor. Once delivered to the cancer cell surface, Vintafolide is internalized into the cancer cell via endocytosis, a natural cellular process. Once inside the cell, Endocyte’s proprietary linker technology releases the chemotherapy to eliminate the cancer cell.
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