Viomicina

Viomicina Uses, Dosage, Side Effects, Food Interaction and all others data.

Viomicina is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomicina was derived from the actinomycete Streptomyces puniceus.

Trade Name Viomicina
Generic Viomycin
Viomycin Other Names Vinacetin A, Viomicina, Viomycin, Viomycine, Viomycinum
Type
Formula C25H43N13O10
Weight Average: 685.69
Monoisotopic: 685.325584661
Groups Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Viomicina
Viomicina

Uses

Viomicina is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.

How Viomicina works

Viomicina binds to a site on the ribosome which lies at the interface between helix 44 of the small ribosomal subunit and helix 69 of the large ribosomal subunit. The structures of this complexes suggest that the viomycin inhibits translocation by stabilizing the tRNA in the A site in the pretranslocation state. This inhibits protein synthesis.

Innovators Monograph

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*** Taking medicines without doctor's advice can cause long-term problems.
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