Ala Hist IR

Ala Hist IR Uses, Dosage, Side Effects, Food Interaction and all others data.

Ala Hist IR maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Ala Hist IR is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Trade Name Ala Hist IR
Availability Over the counter
Generic Dexbrompheniramine
Dexbrompheniramine Other Names d-brompheniramine, Desbrofeniramina, Dexbromfeniramina, Dexbrompheniramin, Dexbromphéniramine, Dexbrompheniramine, Dexbrompheniraminum
Related Drugs hydroxyzine, loratadine, levocetirizine, Vistaril, Atarax, Xyzal
Weight 2mg/5ml, 2mg,
Type Oral liquid, oral tablet
Formula C16H19BrN2
Weight Average: 319.239
Monoisotopic: 318.073161265
Groups Approved
Therapeutic Class
Manufacturer
Available Country United States
Last Updated: September 19, 2023 at 7:00 am
Ala Hist IR
Ala Hist IR

Uses

Ala Hist IR is an antihistamine used to treat allergy symptoms including upper respiratory tract symptoms.

For treatment and relief of symptoms of allergies, hay fever, and colds

Ala Hist IR is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Upper respiratory tract hypersensitivity reaction, site unspecified

How Ala Hist IR works

Ala Hist IR competitively binds to the histamine H1-receptor. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

Toxicity

Signs of an overdose include fast or irregular heartbeat, mental or mood changes, tightness in the chest, and unusual tiredness or weakness.

Food Interaction

  • Avoid alcohol. Taking with alcohol may increase drowsiness.

[Moderate] GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents.

Use in combination may result in additive central nervous system depression and
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol.

Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

Elimination Route

Antihistamines are well absorbed from the gastrointestinal tract after oral administration.

Half Life

25 hours

Innovators Monograph

You find simplified version here Ala Hist IR

*** Taking medicines without doctor's advice can cause long-term problems.
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