Alanosina
Alanosina Uses, Dosage, Side Effects, Food Interaction and all others data.
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Trade Name | Alanosina |
Generic | Alanosine |
Alanosine Other Names | Alanosina, Alanosine, Alanosinum, L-Alanosine |
Type | |
Formula | C3H7N3O4 |
Weight | Average: 149.1054 Monoisotopic: 149.043655727 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in brain cancer and cancer/tumors (unspecified).
How Alanosina works
L-alanosine inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate, an intermediate in purine metabolism. L-alanosine-induced disruption of de novo purine biosynthesis is potentiated by methylthioadenosine phosphorylase (MTAP) deficiency.
Innovators Monograph
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