Aluminium Oxide + Magnesium Trisilicate

Aluminium Oxide + Magnesium Trisilicate Uses, Dosage, Side Effects, Food Interaction and all others data.

Aluminum hydroxide neutralizes stomach hydrocloride to form AICI3 salt plus water; increases gastric pH.

Magnesium Trisilicate neutralizes gastric acidity by increasing gastric pH

Trade Name Aluminium Oxide + Magnesium Trisilicate
Generic Aluminium Oxide + Magnesium Trisilicate
Type
Therapeutic Class Antacid with laxative action, Antacids
Manufacturer
Available Country Bangladesh
Last Updated: September 24, 2024 at 5:38 am
Aluminium Oxide + Magnesium Trisilicate
Aluminium Oxide + Magnesium Trisilicate

Uses

Aluminium Oxide & Magnesium Trisilicate is used for Heartburn, Indigestion, Gastric Hyperacidity, Peptic ulcer disease, Gastroesophageal reflux disorder (GERD)

Aluminium Oxide + Magnesium Trisilicate is also used to associated treatment for these conditions: Acid Reflux, Acid indigestion, Bloating, Colic, Flatulence, Gastric Ulcer, Heartburn, Upset stomach

How Aluminium Oxide + Magnesium Trisilicate works

The gelatinous silicon dioxide, formed by the reaction of magnesium trisilicate with gastric contents is said to protect ulcerated mucosal surfaces and favor healing.

Dosage

Aluminium Oxide + Magnesium Trisilicate dosage

Take 2-4 teaspoonful after meals and at bedtime as needed (up to 4 times a day)

Side Effects

Diarrhoea, constipation, nausea, vomiting.

Toxicity

Adequate doses of magnesium trisilicate may cause diarrhea due to the action of soluble magnesium salts in the enteric tract. Approx 5% of the magnesium is absorbed.

Precaution

Renal dysfunction, low phosphate diet, prolonged use.

Interaction

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.

Magnesium Trisilicate: None well documented.

Volume of Distribution

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track.

Elimination Route

The hydrated silicon dioxide formed in the stomach and passes into the intestinal track where, silica can be partly absorbed.

Half Life

16-20 hours

Clearance

Maximum magnesium clearance is directly proportional to creatinine clearance.

Elimination Route

Excreted in the urine.

Pregnancy & Breastfeeding use

Pregnancy Category- Not Classified. FDA has not yet classified the drug into a specified pregnancy category.

Contraindication

Hypophosphataemia

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*** Taking medicines without doctor's advice can cause long-term problems.
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