Anisotropine Methylbromide

Anisotropine Methylbromide Uses, Dosage, Side Effects, Food Interaction and all others data.

Anisotropine Methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate. Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to inhibit gastric acid secretion.

Table Of contents

• Anisotropine Methylbromide
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Anisotropine Methylbromide
Generic	Anisotropine methylbromide
Anisotropine methylbromide Other Names	Anisotropine methobromide, Anisotropine methylbromide, Méthylbromure d'octatropine, Methyloctatropine bromide, Metilbromuro de octatropina, Octatropine methylbromide, Octatropini methylbromidum
Type
Formula	C17H32BrNO2
Weight	Average: 362.345 Monoisotopic: 361.16164192
Protein binding	Not Known
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

For use in conjunction with antacids or histamine H₂-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.

How Anisotropine Methylbromide works

Quaternary ammonium compounds such as anisotropine methylbromide inhibit the muscarinic actions of acetylcholine on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These postganglionic receptor sites are present in the autonomic effector cells of the smooth muscle, cardiac muscle, sinoatrial and atrioventricular nodes, and exocrine glands.

Elimination Route

Gastrointestinal absorption is poor and irregular. Total absorption after an oral dose is about 10 to 25%.

Half Life

Not Known

Innovators Monograph

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