Antrafenine
Antrafenine Uses, Dosage, Side Effects, Food Interaction and all others data.
Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. It is not widely used as it has largely been replaced by newer drugs.
Its mode of action is not fully understood; however, its ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect.
| Trade Name | Antrafenine |
| Generic | Antrafenine |
| Antrafenine Other Names | Antrafenine |
| Type | |
| Formula | C30H26F6N4O2 |
| Weight | Average: 588.5435 Monoisotopic: 588.195995326 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Antrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain.
How Antrafenine works
Antrafenine is believed to be associated with the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins necessary for normal gastrointestinal and renal function. The inducible cyclooxygenase, COX-2, generates prostaglandins involved in inflammation. Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti-inflammatory activity.
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