Chenodeoxycholoyltaurine
Chenodeoxycholoyltaurine Uses, Dosage, Side Effects, Food Interaction and all others data.
Chenodeoxycholoyltaurine is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to increase bile discharge into the duodenum. It is also being investigated for its role in inflammation and cancer therapy.
| Trade Name | Chenodeoxycholoyltaurine |
| Generic | Taurochenodeoxycholic acid |
| Taurochenodeoxycholic acid Other Names | Chenodeoxycholoyltaurine, Taurine chenodeoxycholate, Taurochenodeoxycholate, Taurochenodeoxycholic acid |
| Type | |
| Formula | C26H45NO6S |
| Weight | Average: 499.704 Monoisotopic: 499.296758867 |
| Groups | Experimental |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Chenodeoxycholoyltaurine is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy.
How Chenodeoxycholoyltaurine works
Chenodeoxycholic acid is a primary bile acid in the liver that combines with taurine to form the bile acid taurochenodeoxycholic acid. In the bile, taurochenodeoxycholic acid is either a sodium (most) or potassium salt. Chenodeoxycholoyltaurine is normally produced in the liver, and its physiologic function as a bile salt is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to increase bile discharge into the duodenum. The mechanism of action of taurochenodeoxycholic acid in inflammation and cancer has yet to be determined.
Innovators Monograph
You find simplified version here Chenodeoxycholoyltaurine
