Chromium(3+) Trichloride

Chromium(3+) Trichloride Uses, Dosage, Side Effects, Food Interaction and all others data.

Chromium(3+) Trichloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

Trivalent chromium is part of glucose tolerance factor, an essential activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function. Providing chromium during TPN helps prevent deficiency symptoms including impaired glucose tolerance, ataxia, peripheral neuropathy and a confusional state similar to mild/moderate hepatic encephalopathy.

Chromium(3+) Trichloride
Uses
Dosage
Side Effect
Precautions
Interactions
Uses during Pregnancy
Uses during Breastfeeding
Accute Overdose
Food Interaction
Half Life
Volume of Distribution
Clearance
Interaction With other Medicine
Contradiction
Storage

Trade Name	Chromium(3+) Trichloride
Generic	Chromic chloride
Chromic chloride Other Names	Chromium chloride, Chromium trichloride, chromium(3+) trichloride, Chromium(III) chloride, Puratronic chromium chloride, Trichlorochromium
Type
Formula	Cl₃Cr
Weight	Average: 158.355 Monoisotopic: 156.847070025
Protein binding	Chromic chloride-induced binding of protein to red cells.
Groups	Approved
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Chromium(3+) Trichloride is a supplement to intravenous solutions given for total parenteral nutrition (TPN).

For use as a supplement to intravenous solutions given for total parenteral nutrition (TPN).

Chromium(3+) Trichloride is also used to associated treatment for these conditions: Total parenteral nutrition therapy

How Chromium(3+) Trichloride works

Metallic chromium has no biological activity. Chromium is referred as a glucose tolerance factor. This glucose tolerance factor is a complex of molecules. Glycine, cysteine, glutamic acid and nicotinic acid along with chromium form this complex.

Toxicity

Reported toxic reactions to chromium include nausea, vomiting, ulcers of the gastrointestinal tract, renal and hepatic damage, convulsions and coma. The acute LD50 for intravenous trivalent chromium in rats was reported as 10 to 18 mg/kg.

Food Interaction

Administer vitamin supplements. Niacin (from food or supplements) may increase the absorption of chromium.
Take with foods containing vitamin C. Vitamin C may increase the oral absorption of chromium/chromic chloride.