Ciluprevir
Ciluprevir Uses, Dosage, Side Effects, Food Interaction and all others data.
The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
| Trade Name | Ciluprevir |
| Generic | Ciluprevir |
| Ciluprevir Other Names | Ciluprevir |
| Type | |
| Formula | C40H50N6O8S |
| Weight | Average: 774.925 Monoisotopic: 774.341083296 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in hepatitis (viral, C).
How Ciluprevir works
A distinguishing feature of the BILN 2061 inhibitor series is the presence of C-terminal carboxylic acid functionality. This provides exquisite selectivity with respect to other proteases, a property not easily attained with more conventional classes of covalent, reversible serine protease inhibitors. BILN 2061 blocks NS3 protease-dependent polyprotein processing in HCV replicon-containing cells. It is orally bioavailable in various animal species.
Innovators Monograph
You find simplified version here Ciluprevir
