Copexa

Copexa Uses, Dosage, Side Effects, Food Interaction and all others data.

Copexa is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease. It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body.

Copexa demonstrated the ability to reduce toxic free copper levels and substantially improve clinical neurologic outcomes in Wilson’s patients. Studies also showed it is capable of specifically inhibiting chronic fibrotic disease processes in the lung.

Trade Name Copexa
Generic Tetrathiomolybdate
Tetrathiomolybdate Other Names Thiomolybdate, Tiomolibdate ion
Type
Formula MoS4
Weight Average: 224.19
Monoisotopic: 225.794787
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Copexa
Copexa

Uses

Investigated for use/treatment in liver disease and pulmonary fibrosis.

How Copexa works

Copexa has demonstrated the ability to inhibit fibrosis in a number of well established animal models through the sequestration of available copper and inhibition of key fibrotric cytokines, including secreted protein acid rich in cysteine (SPARC), NFkappaB, TGF-beta, FGF-2, IL-1, IL-6, IL-8, and connective tissue growth factor (CTGF).

Innovators Monograph

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