Cyclergine
Cyclergine Uses, Dosage, Side Effects, Food Interaction and all others data.
A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclergine is not approved for use in the U.S. or Canada, but is approved in various European countries.
Cyclergine is in a class of drugs called vasodilators. Cyclergine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.
| Trade Name | Cyclergine |
| Availability | Discontinued |
| Generic | Cyclandelate |
| Cyclandelate Other Names | Ciclandelato, Cyclandelate, Cyclandelatum |
| Related Drugs | amlodipine, nitroglycerin, nifedipine, Norvasc, prazosin, doxazosin, vitamin e, Alpha E, E-400 Clear |
| Type | |
| Formula | C17H24O3 |
| Weight | Average: 276.3707 Monoisotopic: 276.172544634 |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Cyclergine is a vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
How Cyclergine works
Cyclergine produces peripheral vasodilation by a direct effect on vascular smooth muscle. Pharmacological action may be due to calcium-channel antagonism.
Toxicity
Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
Food Interaction
- Take with food. Food reduces irritation.
Cyclergine Disease Interaction
Moderate: coronary artery/CV disease, glaucoma, prolonged bleeding
Elimination Route
Well absorbed following oral administration.
Innovators Monograph
You find simplified version here Cyclergine
