Incel
Incel Uses, Dosage, Side Effects, Food Interaction and all others data.
The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Incel dicitrate blocks two major multi-drug resistance mechanisms: P-glycoprotein (MDR-1) and multi-drug resistance-associated protein (MRP).
Trade Name | Incel |
Generic | Biricodar |
Biricodar Other Names | Biricodar |
Type | |
Formula | C34H41N3O7 |
Weight | Average: 603.716 Monoisotopic: 603.294450672 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Administered intravenously, biricodar dicitrate is to be used in combination with cancer chemotherapy agents.
How Incel works
Vertex’s research shows that biricodar dicitrate can enhance the accumulation of chemotherapy agents in tumor cells by blocking the drug pumps P-gp and MRP, and that it is capable of restoring the sensitivity of tumors to treatment with chemotherapeutic agents.
Innovators Monograph
You find simplified version here Incel