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Fenazon Uses, Dosage, Side Effects and more

An analgesic and antipyretic that has been given by mouth and as ear drops. Fenazon is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Fenazon is an analgesic and antipyretic that has been given by mouth and as ear drops. Fenazon is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Attribute Details
Trade Name Fenazon
Generic Antipyrine
Antipyrine Other Names Analgesine, Antipyrine, Fenazon, Fenazona, Phenazon, Phenazone
Type
Formula C11H12N2O
Weight Average: 188.2258
Monoisotopic: 188.094963016
Groups Approved, Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am
   

Uses

Fenazon is an antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.

Fenazon is an analgesic often used to test effects of other drugs on liver enzymes.

In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies.

Fenazon is also used to associated treatment for these conditions: Cough, Otitis Media (OM), Buccopharyngeal anesthesia

How Fenazon works

Fenazon is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis.

Food Interaction

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