Ferric sulfate
Ferric sulfate Uses, Dosage, Side Effects, Food Interaction and all others data.
Ferric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. It is used in different fields such as dermatology, dentistry and it is thought to present hemostatic properties by interacting chemically with blood proteins. By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category (Generally Recognized As Safe).
The administration of ferric sulfate as a dermatologic agent has showed delayed reepithelialization and dyspigmentation. Some studies have reported the generation of inflammation in the sites of administration of ferric sulfate.
| Trade Name | Ferric sulfate |
| Generic | Ferric sulfate |
| Ferric sulfate Other Names | Ferric sulfate |
| Type | |
| Formula | Fe2H10O17S3 |
| Weight | Average: 489.93 Monoisotopic: 489.777884 |
| Protein binding | Ferric sulfate presents very high protein binding properties, this property is thought to be due to its acidic profile. |
| Groups | Approved |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
Uses
Ferric sulfate is a medication used as a coagulant and hemostatic agent.
Ferric sulfate was first used in dermatology as part of the Monsel's solution. This solution is an antihemorrhagic agent used in skin and mucosal biopsies. The use of ferric sulfate in dermatology is under review as ferric sulfate is corrosive and injurious and it can cause degenerative changes that are not observed with other alternatives like collagen.
Ferric sulfate is also used as a coagulative and hemostatic agent. It is a mechanic hemostatic agent used directly on the damaged tissue.
In dentistry, ferric sulfate is used as a pulpotomy medicament to control pulpal bleeding, as an antibacterial agent and as a hemostatic reagent for restorative dentistry, for postextraction hemorrhage and for periradicular and endodontic surgery.
How Ferric sulfate works
The main function of ferric sulfate is as a hemostatic agent in different medical practices. This hemostatic function is achieved when ferric sulfate is applied directly in the damaged tissue. Once applied, ferric sulfate forms ferric ion-protein complex which helps the sealing of the damaged vessels mechanically. The formation of agglutinated protein complexes produces the generation of occlusion in the capillary orifices. The formation of the ferric protein complex is thought to be due to a chemical reaction between the acidic form of ferric sulfate and the blood proteins.
Toxicity
Ferric sulfate has been proven to be an irritating substance into the eye, throat, gastrointestinal and respiratory tract.
Food Interaction
No interactions found.Volume of Distribution
Pharmacokinetic studies related to the volume of distribution of ferric sulfate have not been performed.
Elimination Route
Pharmacokinetic studies related to the absorption of ferric sulfate have not been performed.
Half Life
Pharmacokinetic studies related to the half-life of ferric sulfate have not been performed.
Clearance
Pharmacokinetic studies related to the clearance of ferric sulfate have not been performed.
Elimination Route
Pharmacokinetic studies related to the elimination of ferric sulfate have not been performed.
Innovators Monograph
You find simplified version here Ferric sulfate
