Flumétasone
Flumétasone Uses, Dosage, Side Effects, Food Interaction and all others data.
Flumétasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Flumétasone pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Trade Name | Flumétasone |
Generic | Flumethasone |
Flumethasone Other Names | Flumetasona, Flumétasone, Flumetasone, Flumetasonum, Flumethasone |
Type | |
Formula | C22H28F2O5 |
Weight | Average: 410.458 Monoisotopic: 410.190480328 |
Groups | Approved, Vet approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Flumétasone is a corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
For the treatment of contact dermatitis, atopic dermatitis, exczema, psoriasis, diaper rash and other skin conditions
Flumétasone is also used to associated treatment for these conditions: Atopic Dermatitis (AD), Atopic Dermatitis (AD) of the external ear canal, Cradle Cap, Dermatitis, Dermatosis, Discoid Lupus Erythematosus (DLE), Infantile Eczema, Inflammatory Skin Disease, Intertrigo, Lichen Planus (LP), Neurodermatitis, Otitis Externa, Psoriasis Vulgaris (Plaque Psoriasis), Radiodermatitis, Solar erythema, Corticosteroid-responsive dermatoses, Intertriginous erythema of the anogenital, Otomycosis caused by Aspergillus niger, Resistant to other corticosteroids Dermatosis
How Flumétasone works
Flumétasone is a glucocorticoid receptor agonist. This complex binds to the nucleus causing a variety of genetic activation and repressions. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Flumétasone binds to plasma transcortin, and it becomes active when it is not bound to transcortin.
Toxicity
Can lead to signs of irritation such as burning sensation, itching or skin rash at the site of application; hypersensitivity reactions.
Food Interaction
No interactions found.Elimination Route
Minimal if applied topically
Innovators Monograph
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