Histalean
Histalean Uses, Dosage, Side Effects, Food Interaction and all others data.
Histalean is a new weight loss drug developed by Obecure Ltd. It is a new formulation that is based on the vertigo medication, Betahistine. Obecure is repurposing betahistine, which is an H1 receptor agonist and partial H3 receptor antagonist for the treatment of obese individuals and for other weight management indications.
Trade Name | Histalean |
Generic | OBE101 |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in adverse effects (drug), hyperlipidemia, and obesity.
How Histalean works
Histalean is a H1 receptor agonist and partial H3 receptor antagonist. Because inhibition of H1 receptors increases feeding, agonism of H1 receptors by Histalean should reduce feeding. By also partially antagonizing H3, Histalean impedes a negative feedback loop that essentially prolongs stimulation of the H1 receptors.
Innovators Monograph
You find simplified version here Histalean