Iclaprim
Iclaprim Uses, Dosage, Side Effects, Food Interaction and all others data.
Trade Name | Iclaprim |
Generic | Iclaprim |
Iclaprim Other Names | Iclaprim |
Type | |
Formula | C19H22N4O3 |
Weight | Average: 354.41 Monoisotopic: 354.169190584 |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia.
How Iclaprim works
Iclaprim is a novel diaminopyrimidine, and an inhibitor of dihydrofolate reductase, which has shown potent, extended-spectrum in vitro activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, vancomycin-intermediate and vancomycin-resistant S. aureus and macrolide-, quinolone- and trimethoprim-resistant strains. In addition, iclaprim has demonstrated activity against Streptococcus pneumoniae including penicillin-, erythromycin-, levofloxacin- and trimethoprim/sulfamethoxazole-resistant strains.
Innovators Monograph
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