MedicinesFAQ

Ifosfamide Mustard Uses, Dosage, Side Effects and more

Ifosfamide Mustard (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.

Attribute Details
Trade Name Ifosfamide Mustard
Generic Palifosfamide
Palifosfamide Other Names Ifosfamide mustard, Ifosforamide mustard, Isophosphamide mustard, Isophosphoramide mustard, Palifosfamide
Type
Formula C4H11Cl2N2O2P
Weight Average: 221.022
Monoisotopic: 219.993519532
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: January 7, 2025 at 1:49 am
   

Uses

Investigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.

How Ifosfamide Mustard works

After metabolic activation, palifosfamide alkylates or binds with many intracellular molecular structures, including nucleic acids. The cytotoxic action is primarily due to cross-linking of strands of DNA and RNA, as well as inhibition of protein synthesis.

Innovators Monograph

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