IgM-enriched Immunoglobulins Uses, Dosage, Side Effects and more
IgM-enriched Immunoglobulins, also known as IgM-enriched immunoglobulin, falls under a group of polyclonal immunoglobulin preparations. It is comprised of immunoglobulin G (IgG) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).
Trade Name | IgM-enriched Immunoglobulins |
Generic | Pentaglobin |
Pentaglobin Other Names | IgM-enriched immunoglobulins, IVIgGM |
Type | |
Groups | Investigational |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | January 7, 2025 at 1:49 am |
How IgM-enriched Immunoglobulins works
IgM-enriched Immunoglobulins has potential antibacterial and immunomodulatory properties where, compared to immunoglobulin treatments without IgM, pentaglobin may have an increased ability to eliminate infectious pathogens . The IgM in the preparation plays a role in complement activation and neutralization of bacterial endo- and exotoxins. IgM-enriched Immunoglobulins is used as an adjuvant in treatment of severe bacterial infections while it is also investigated against peritonitis, sepsis, and COVID-19.