Megalone
Megalone Uses, Dosage, Side Effects, Food Interaction and all others data.
Megalone is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Megalone is not an inhibitor of CYP1A2.
Megalone is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
Trade Name | Megalone |
Generic | Fleroxacin |
Fleroxacin Other Names | Fleroxacin, Fleroxacine, Fleroxacino, Fleroxacinum, Fleroxicin |
Type | |
Formula | C17H18F3N3O3 |
Weight | Average: 369.344 Monoisotopic: 369.130025941 |
Groups | Experimental |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Megalone is a broad-spectrum antimicrobial fluoroquinolone.
How Megalone works
The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination.
Food Interaction
- Avoid milk and dairy products.
- Limit caffeine intake.
- Take with a full glass of water.
- Take with or without food.
Elimination Route
Rapidly and well absorbed from the gastrointestinal tract after oral administration.
Innovators Monograph
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