Megalone

Megalone Uses, Dosage, Side Effects, Food Interaction and all others data.

Megalone is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Megalone is not an inhibitor of CYP1A2.

Megalone is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.

Trade Name Megalone
Generic Fleroxacin
Fleroxacin Other Names Fleroxacin, Fleroxacine, Fleroxacino, Fleroxacinum, Fleroxicin
Type
Formula C17H18F3N3O3
Weight Average: 369.344
Monoisotopic: 369.130025941
Groups Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Megalone
Megalone

Uses

Megalone is a broad-spectrum antimicrobial fluoroquinolone.

How Megalone works

The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination.

Food Interaction

  • Avoid milk and dairy products.
  • Limit caffeine intake.
  • Take with a full glass of water.
  • Take with or without food.

Elimination Route

Rapidly and well absorbed from the gastrointestinal tract after oral administration.

Innovators Monograph

You find simplified version here Megalone

*** Taking medicines without doctor's advice can cause long-term problems.
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