Menthyl-O-aminobenzoate
Menthyl-O-aminobenzoate Uses, Dosage, Side Effects, Food Interaction and all others data.
Menthyl-O-aminobenzoate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Menthyl-O-aminobenzoate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.
Menthyl-O-aminobenzoate effect provides a low-level, broad-spectrum protecting coverage effect.
Trade Name | Menthyl-O-aminobenzoate |
Generic | Meradimate |
Meradimate Other Names | Menthyl anthranilate, Menthyl-O-aminobenzoate, Meradimate |
Type | |
Formula | C17H25NO2 |
Weight | Average: 275.392 Monoisotopic: 275.188529049 |
Protein binding | As meradimate is not absorbed, this pharmacokinetic property is not relevant. |
Groups | Approved |
Therapeutic Class | |
Manufacturer | |
Available Country | |
Last Updated: | September 19, 2023 at 7:00 am |
Uses
Menthyl-O-aminobenzoate is an ingredient used in sunscreens to absorb UV radiation.
Menthyl-O-aminobenzoate is used as an active ingredient in sunscreens or as a sunblock factor in different products. It fits under the category of broad-spectrum absorbent agent. These characteristics are important to consider due to the fact that this kind of ingredients can either absorb or reflect UV radiation. It is also important to know the type of rays that cover. UVA rays are the responsible of causing sun damage and reaching deeper layers of the skin while UVB can only cause sunburn in the outer layer of the skin. When an agent is of broad spectrum, this means that this agent is capable of acting in both UVA and UVB rays.
Menthyl-O-aminobenzoate is also used to associated treatment for these conditions: UV protection
How Menthyl-O-aminobenzoate works
Menthyl-O-aminobenzoate acts by absorbing both the UVA and UVB radiation, this provides this ingredient with a broad spectrum and it explains why it is highly used in different products such as lip balms, lipsticks, and moisturizers. Its protective effective action does not cover completely the UVA rays as it only reaches 336 nm. This has been proven even thought meradimate has a theoretical protective coverage range between 200-380 nm. Its function is related to the intrinsic structure of meradimate which is an ortho-disubstituted aminobenzoate. This structure allows easy electron delocalization and shifts in the maximum absorption.
Toxicity
Menthyl-O-aminobenzoate is considered safe but some studies have shown that it can increase the production of reactive oxygen species.
Food Interaction
No interactions found.Volume of Distribution
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
Elimination Route
Menthyl-O-aminobenzoate is not absorbed through the skin.
Half Life
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
Clearance
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
Elimination Route
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
Innovators Monograph
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