MLN8054
MLN8054 Uses, Dosage, Side Effects, Food Interaction and all others data.
MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.
| Trade Name | MLN8054 |
| Generic | MLN8054 |
| Type | |
| Formula | C25H15ClF2N4O2 |
| Weight | Average: 476.862 Monoisotopic: 476.085159861 |
| Groups | Investigational |
| Therapeutic Class | |
| Manufacturer | |
| Available Country | |
| Last Updated: | September 19, 2023 at 7:00 am |
How MLN8054 works
MLN8054 is a selective small-molecule Aurora A kinase inhibitor that has entered Phase I clinical trials for advanced solid tumors. MLN8054 inhibits recombinant Aurora A kinase activity in vitro and is selective for Aurora A over the family member Aurora B in cultured cells. MLN8054 treatment results in G2/M accumulation and spindle defects and inhibits proliferation in multiple cultured human tumor cells lines.
Innovators Monograph
You find simplified version here MLN8054
