Nifluril

Nifluril Uses, Dosage, Side Effects, Food Interaction and all others data.

Nifluril is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.

Nifluril, a nonsteroidal anti-inflammatory fenamate, is a Ca2+-activated Cl- channel blocker.

Table Of contents

• Nifluril
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Nifluril
Generic	Niflumic acid
Niflumic acid Other Names	Acide niflumique, Acido niflumico, Acidum niflumicum, Niflumic acid
Type
Formula	C13H9F3N2O2
Weight	Average: 282.218 Monoisotopic: 282.061612157
Protein binding	90% bound to plasma proteins.
Groups	Experimental
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Nifluril is a cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.

Used in the treatment of rheumatoid arthritis.

Nifluril is also used to associated treatment for these conditions: Inflammation, Pain, Inflammatory, Postoperative Inflammatory Response

How Nifluril works

Nifluril is able to inhibit both phospholipase A2 as well as COX-2, thereby acting as an antiinflamatory and pain reduction agent.

Toxicity

Oral, mouse: LD₅₀ = 350 mg/kg; Oral, rat: LD₅₀ = 250 mg/kg

Elimination Route

Well absorbed following oral administration.

Half Life

2.5 hours

Innovators Monograph

You find simplified version here Nifluril