Noctilan

Noctilan Uses, Dosage, Side Effects, Food Interaction and all others data.

Noctilan is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects. Noctilan has similar effects to short-acting benzodiazepines such as triazolam. Noctilan is indicated for 2-4 weeks of treatment for severe or debilitating insomnia. Noctilan is an extremely potent drug and it is rapidly eliminated with an average half-life of 4.4 hours (range 3.6 - 7.9 hours).

Noctilan is not approved for sale in the UK, United States or Canada but is sold in the Netherlands, Germany, Spain, Belgium, Austria, Portugal, Israel, Italy and Japan.

Table Of contents

• Noctilan
• Uses
• Dosage
• Side Effect
• Precautions
• Interactions
• Uses during Pregnancy
• Uses during Breastfeeding
• Accute Overdose
• Food Interaction
• Half Life
• Volume of Distribution
• Clearance
• Interaction With other Medicine
• Contradiction
• Storage

Trade Name	Noctilan
Generic	Brotizolam
Brotizolam Other Names	Brotizolam, Brotizolamum
Type
Formula	C15H10BrClN4S
Weight	Average: 393.689 Monoisotopic: 391.949807384
Protein binding	The mean value of the free fraction (%): 8.4 ± 0.7.
Groups	Investigational, Withdrawn
Therapeutic Class
Manufacturer
Available Country
Last Updated:	September 19, 2023 at 7:00 am

Uses

Noctilan is a benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia.

Noctilan is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia.

Noctilan is also used to associated treatment for these conditions: Insomnia

Volume of Distribution

0.63 l/kg.

Elimination Route

The plasma concentration profile of brotizolam can be described as a one compartmental open model with first-order absorption.

Half Life

4.4 hours.

Clearance

Total clearance: 109 ml/min.

Innovators Monograph

You find simplified version here Noctilan