Noscapine HCl

Noscapine HCl Uses, Dosage, Side Effects, Food Interaction and all others data.

Trade Name Noscapine HCl
Generic Noscapine
Noscapine Other Names alpha-Narcotine, Noscapina, Noscapine, Noscapinum
Type
Formula C22H23NO7
Weight Average: 413.4205
Monoisotopic: 413.147452095
Groups Approved, Investigational
Therapeutic Class
Manufacturer Pharmachemie
Available Country Netherlands
Last Updated: September 19, 2023 at 7:00 am
Noscapine HCl
Noscapine HCl

Uses

Noscapine HCl is a non-sedating isoquinoline alkaloid used primarily for its antitussive properties.

Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma.

Noscapine HCl is also used to associated treatment for these conditions: Common Cold, Cough, Respiratory Diseases, Airway secretion clearance therapy

How Noscapine HCl works

Noscapine HCl's antitussive effects appear to be primarily mediated by its sigma receptor agonist activity. Evidence for this mechanism is suggested by experimental evidence in rats. Pretreatment with rimcazole, a sigma specific antagonist, causes a dose-dependent reduction in antitussive activity of noscapine.

Innovators Monograph

You find simplified version here Noscapine HCl

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