Oregovamab

Oregovamab Uses, Dosage, Side Effects, Food Interaction and all others data.

Oregovamab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.

Oregovamab is well tolerated and induces multiple antigen-specific immune responses, maintained during concomitant chemotherapy. A significant survival benefit has been observed in patients mounting a T-cell response to CA125 and/or autologous tumor. Vaccination with oregovomab may stimulate a host cytotoxic immune response against tumor cells that express CA125.

Trade Name Oregovamab
Generic Oregovomab
Oregovomab Other Names Monoclonal antibody B43.13, Oregovamab, Oregovomab
Type
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Oregovamab
Oregovamab

Uses

Investigated for use/treatment in ovarian cancer.

How Oregovamab works

Oregovamab targets the circulating tumour-associated antigen CA 125, which is shed from the surface of human ovarian cancer cells; the antibodies induce broad cellular and humoral immune responses against CA 125 via complex formation. Unlike free CA 125, CA 125-oregovomab complexes can prime dendritic cells, leading to downstream activation of T cells.

Innovators Monograph

You find simplified version here Oregovamab

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