Oxoallopurinol

Oxoallopurinol Uses, Dosage, Side Effects, Food Interaction and all others data.

Oxoallopurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.

Trade Name Oxoallopurinol
Generic Oxypurinol
Oxypurinol Other Names Alloxanthine, DHPP, Ossipurinolo, Oxipurinol, Oxipurinolum, Oxoallopurinol, Oxypurinol
Type
Formula C5H4N4O2
Weight Average: 152.1109
Monoisotopic: 152.033425392
Groups Investigational
Therapeutic Class
Manufacturer
Available Country
Last Updated: September 19, 2023 at 7:00 am
Oxoallopurinol
Oxoallopurinol

Uses

Intended for the treatment of congestive heart failure and hyperuricemia.

How Oxoallopurinol works

Oxoallopurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the blood and urine. Oxoallopurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, resulting in further reductions of serum uric acid concentrations.

Half Life

23.3 +/- 6.0 hours

Innovators Monograph

You find simplified version here Oxoallopurinol

*** Taking medicines without doctor's advice can cause long-term problems.
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